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1:00
YouTube
MedLecturesMadeEasy
Mechanism of essential hypertension
Early stage: multifactorial etiology → overactivity of renin-angiotensin- aldosterone system → sympathetic nervous system overactivity → increase in cardiac output Later stage: increase in vascular smooth muscle intracellular calcium → vascular hypertrophy → increase in systemic vascular resistance → cardiac output returns to normal ...
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