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med's go on Instagram: "Lithium toxicity is often precipitated by drugs that reduce renal clearance of lithium, since lithium is almost entirely excreted by the kidneys. Thiazide diuretics like hydrochlorothiazide increase sodium loss, leading to compensatory proximal tubule reabsorption of sodium—and lithium follows the same pathway—causing elevated lithium levels. This can produce confusion, ataxia, slurred speech, and coarse tremor. Other listed medications do not significantly affect lithium
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